Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5278327 | Tetrahedron Letters | 2011 | 4 Pages |
Abstract
The condensation of 2-aminobenzamide with aldehydes or ketones has been achieved using cellulosesulfonic acid under mild reaction conditions to furnish 2,3-dihydroquinazolin-4(1H)-ones in good yields with a high selectivity. The use of biodegradable solid acid catalyst, cellulosesulfonic acid makes this method quite simple, more convenient, and practical. This catalyst was also found to be very active for the synthesis of hydroxyalkylquinazolin-4-ones from cyclic enol ethers.
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Organic Chemistry
Authors
B.V. Subba Reddy, A. Venkateswarlu, Ch. Madan, A. Vinu,