Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5278432 | Tetrahedron Letters | 2006 | 4 Pages |
Abstract
A unique 1,3-dioxonium cation facilitated Ritter-type reaction was discovered when glycerol dipivaloates were treated with strong acid in acetonitrile. The stereoselectivity and regioselectivity of this new Ritter-type reaction were further explored by using erythritol tripivaloate and 1,2,4-butanetriol dipivaloate as the substrates. Several protected aminopolyols were generated as important chiral building blocks. This reaction was employed to synthesize a protected aminosugar lactone.
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Xuezheng Song, Rawle I. Hollingsworth,