| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5278445 | Tetrahedron Letters | 2008 | 5 Pages |
Abstract
A regioselective method for the bromination of phenols, ethers and anilines using a ZrBr4/diazene mixture is described. The reaction takes place under mild reaction conditions and the bromine atom adds first at the para unsubstituted position with respect to the OH, OR or NR2 group of the activated aromatic substrate. Less reactive compounds such as toluene, phenyl acetate, benzonitrile and trifluoromethylbenzene remain intact under the same conditions.
Graphical abstractA regioselective method for the bromination of phenols, ethers and anilines using a ZrBr4/diazene mixture is described.Download full-size image
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Tadej Stropnik, Sergeja Bombek, Marijan KoÄevar, Slovenko Polanc,