Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5278479 | Tetrahedron Letters | 2008 | 4 Pages |
Abstract
Herein, we report efficient catalysts based on phosphoramidites for the asymmetric copper-catalyzed conjugate addition of Grignard reagents to acyclic α,β-unsaturated ketones. A variety of Grignard reagents can be added to aliphatic and aromatic acyclic enones with good yields and moderate to good enantioselectivities.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Beatriz Maciá, M. Ángeles Fernández-Ibáñez, NataÅ¡a MrÅ¡iÄ, Adriaan J. Minnaard, Ben L. Feringa,