| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5278516 | Tetrahedron Letters | 2009 | 4 Pages |
Abstract
We describe the use of a microwave reaction for the conversion of various bromides to sodium sulfonates that have been further elaborated to sulfonyl chlorides. This new approach leads to much improved yields and shorter reaction times. Representative sulfonyl chlorides serve as precursors for the respective sulfonyl fluorides that are potent inhibitors of the fatty acid amide hydrolase.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Shakiru O. Alapafuja, Spyros P. Nikas, Vidyanand G. Shukla, Ioannis Papanastasiou, Alexandros Makriyannis,