| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5278556 | Tetrahedron Letters | 2011 | 4 Pages |
Abstract
A three-step method was developed to convert N-1 unprotected 3-substituted indoles to 3-substituted 2-acylaminoindoles. Established indole chlorination chemistry was employed to generate stable 2-trifluoroacetylamino indoles, which were subsequently deprotected and selectively acylated.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
John E. Mangette, Xuemei Chen, Ravi Krishnamoorthy, A. Samuel Vellekoop, Adam J. Csakai, Fatoumata Camara, William D. Paquette, Hong-Jun Wang, Hidenori Takahashi, Roman Fleck, Gregory P. Roth,