Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5278592 | Tetrahedron Letters | 2006 | 6 Pages |
Abstract
The amination of a variety of highly functionalized heterocyclic bromides has been accomplished using a CuI/proline catalyst system. The current study significantly expanded the scope of the reaction by using examples relevant to drug discovery programs and has demonstrated reaction rate acceleration using microwave heating.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Vince S.C. Yeh, Paul E. Wiedeman,