| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5278625 | Tetrahedron Letters | 2006 | 5 Pages |
Abstract
We report the first enzyme-catalysed kinetic resolution of epoxy enol esters. The lipase-promoted hydrolysis of these compounds provided α-hydroxyketones or α-hydroxyaldehydes (arising from the spontaneous rearrangement of the epoxy enols) and the residual esters with moderate to good enantioselectivity (E up to 100).
Related Topics
Physical Sciences and Engineering
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Organic Chemistry
Authors
Sébastien Gravil, Henri Veschambre, Robert Chênevert, Jean Bolte,