| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5278647 | Tetrahedron Letters | 2005 | 4 Pages |
Abstract
2,3-Diphenylpropionic acid library for VLA-4 antagonist was synthesized on solid-phase. Comparison of the two synthetic routes via an orthogonal generation of two aromatic amino functional groups are discussed. From this work, several compounds were identified as potent VLA-4 antagonists.
Graphical abstractDownload full-size image
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Yoichiro Hoshina, Satoru Ikegami, Kyoko Fujimoto, Akihiko Okuyama, Tatsuhiro Harada, Susan James, Peter G. Griffiths, Zemin Wu, Michael Lilly, Andrew M. Bray,