Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5278662 | Tetrahedron Letters | 2011 | 4 Pages |
Abstract
The preparation of the novel isomeric 6- and 7-propargyloxy derivatives of 4-(3-fluoroanilino)-quinazoline was achieved using a six-step process. An alternate method to the 7-propargyloxy derivative and analogous 7-propargyloxy containing compounds is also described.
Graphical abstractThe synthesis of 6- and 7-propargyloxy-4-anilinoquinazolines as probes for tyrosine kinases is described.Download full-size image
Related Topics
Physical Sciences and Engineering
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Authors
Helen Trinh Pham, Robert N. Hanson, Sandra L. Olmsted, Anton Kozhushnyan, Adam Visentin, Paul J. Weglinsky, Chris Massero, Kristen Bailey,