Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5278668 | Tetrahedron Letters | 2011 | 4 Pages |
Abstract
An efficient method for the Beckmann rearrangement of ketoximes to amides mediated by a catalytic amount (15 mol %) of propylphosphonic anhydride (T3P®) is described. Aldoximes underwent second order Beckmann rearrangement to provide the corresponding nitriles in excellent yields on reacting with T3P (15 mol %) at room temperature. The main advantages of this environmentally friendly protocol include procedural simplicity, and particularly ease of isolation of the products.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
John Kallikat Augustine, Rajesha Kumar, Agnes Bombrun, Ashis Baran Mandal,