| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5278669 | Tetrahedron Letters | 2011 | 4 Pages |
Cyclopheophorbides are often major chlorophyll-a degradation products in biogeochemical situations. Authentic standards are unavailable and facile generation of pure compounds is required. 132,173-Cyclomesopheophorbide-a-enol (mesoCYCLO) was prepared in moderate yields via a known Dieckmann-like condensation of mesopyropheophorbide-a methyl ester (mpPBIDaME). MesoCYCLO was purified by flash chromatography over a polymeric reversed phase (PRP-1â¢) material, negating the requirement for a crystallization step. Structural verification included ultraviolet-visible spectrometry, high resolution matrix (sulfur/CS2) assisted laser desorption mass spectrometry, and nuclear magnetic resonance.
Graphical abstract132,173-Cyclomesopheophorbide-a-enol (aka 'mesoCYCLO') was hemisynthesized to provide an additional needed standard for biogeochemical studies of chlorophyll diagenesis.Download full-size image
