Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5278773 | Tetrahedron Letters | 2008 | 4 Pages |
Abstract
A facile reductive ring opening of C-aryl pseudoglycals is reported for the first time. The combination of titanium tetrachloride (Lewis acid) and triethylsilane (reducing agent) at â78 °C in dichloromethane is a mild and efficient reagent system for this transformation. The reagent system was successfully tested on various C-aryl pseudoglycal substrates to yield the corresponding ring opened products containing two asymmetric hydroxyls and a cis-double bond.
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Ch. Raji Reddy, G. Balakrishna Reddy, Ch. Lohitha Rao,