| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5278806 | Tetrahedron Letters | 2006 | 4 Pages |
Abstract
Following the thio-conjugate addition of (±)-9, its enantiomers were extremely efficiently discriminated using Novozym 435®. The thio-differentiating unit may then be removed either under reductive conditions, using Raney nickel, or following an oxidation-elimination sequence. In this manner enantioenriched derivatives of 1,1-dioxo-2,3-dihydro-1H-1λ6-thiophen-3-ol 9 may be accessed.
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Ben S. Morgan, Stanley M. Roberts, Paul Evans,