| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5278808 | Tetrahedron Letters | 2006 | 4 Pages |
Abstract
Among various transition metals, iron is nontoxic, cheap and hence of great potential synthetic use. We report herein a water stable chiral Lewis acid containing an iron(II) ion and a pybox-type ligand. The resulting cationic aqua complex of C2-symmetry is an effective Lewis acid catalyst for asymmetric Mukaiyama-aldol reactions in aqueous media. The aldol products have been obtained in good yields, syn-diastereoselectivities and ca. 70% levels of enantioselectivity.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Joanna Jankowska, Joanna Paradowska, Jacek Mlynarski,