| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5278834 | Tetrahedron Letters | 2006 | 5 Pages |
Abstract
A general and convenient synthetic route to various 2-aryl-N-tosylazetidines has been described. Their ZnX2 (X = I, OTf) mediated nucleophilic ring opening with halides and [4+2] cycloaddition reactions with various nitriles have been achieved to afford γ-iodoamines and substituted tetrahydropyrimidines, respectively, in good to excellent yields. A mechanism for the cycloaddition reaction is proposed.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Manas K. Ghorai, Kalpataru Das, Amit Kumar, Animesh Das,