Article ID Journal Published Year Pages File Type
5278858 Tetrahedron Letters 2005 4 Pages PDF
Abstract

A new route to 3,4-disubstituted piperidines was developed using chiral 1,4-dihydropyridines as key intermediates, the synthetic utility of which was demonstrated by formal synthesis of (−)-paroxetine and (+)-femoxetine.

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Physical Sciences and Engineering Chemistry Organic Chemistry
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A new route to 3,4-disubstituted piperidines: formal synthesis of (−)-paroxetine and (+)-femoxetine
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