| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5278861 | Tetrahedron Letters | 2005 | 5 Pages |
Abstract
An economical, simple, and efficient direct aldol reaction via the double activation of both aldehydes and ketones by ammonia has been developed. An unprecedented tandem Mannich reaction was observed when hydroxybenzaldehydes, pyrrole-2-carboxyaldehyde, and indole-3-carboxyaldehyde were employed to afford 2,2-dimethyl-6-aryl-4-pyrilidinones in moderate to good yields.
Graphical abstractDownload full-size image
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Lichun Feng, Lijin Xu, Kimhung Lam, Zhongyuan Zhou, C.W. Yip, Albert S.C. Chan,