| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5278918 | Tetrahedron Letters | 2011 | 4 Pages |
Abstract
The epimerization of chiral lactides was studied in the presence of various homogeneous and heterogeneous bases. Some solvent/base systems were found to promote epimerization at room temperature efficiently. Side reactions such as polymerization were not observed or occurred only slowly. This new protocol offers the opportunity of the transformation of meso-lactide into rac-lactide. Therefore it can reduce the overall manufacturing costs of polylactides, a problem which currently hampers the broad application of those environmentally friendly polymers in a large scale.
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Ivan A. Shuklov, Haijun Jiao, Joachim Schulze, Wolfgang Tietz, Klaus Kühlein, Armin Börner,