| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5278936 | Tetrahedron Letters | 2007 | 4 Pages |
Abstract
4-Propargyl-2-azetidinone and 4-allenyl-2-azetidinone derivatives can be facilely obtained from 4-acetoxy-2-azetidinone and propargyl bromides via zinc-mediated Barbier-type reaction. A new method has been developed to construct the carbapenem bicyclic nucleus by cyclization of 4-propargyl-2-azetidinone and 4-allenyl-2-azetidinone derivatives catalyzed by PtCl2.
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Authors
Biao Jiang, Hua Tian,