Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5278956 | Tetrahedron Letters | 2007 | 4 Pages |
Abstract
The first total synthesis and structural determination of (+)-BE-52440A have been achieved by enantiodivergent synthesis. S-Bridging dimerization including SN2 epoxy-opening reaction of tetrasubstituted epoxide 2 with sodium sulfide has been achieved in excellent yield with high regioselectivity. The structure of (+)-BE-52440A was determined to be the dimer of kalafungin type pyranonaphthoquinone.
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