| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5279002 | Tetrahedron Letters | 2009 | 4 Pages |
Abstract
We report copper-catalyzed intramolecular cyclization of 8-alkynyl-1,2,3,4-tetrahydroquinolines, obtained via a Pd/C-mediated Sonogashira coupling in water, to afford 2-substituted 5,6-dihydro-4H-pyrrolo[3,2,1-ij]quinolines. Further functionalization of the compounds synthesized was carried out under Heck, Sonogashira, and Suzuki reaction conditions.
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
![C-N bond forming reaction under copper catalysis: a new synthesis of 2-substituted 5,6-dihydro-4H-pyrrolo[3,2,1-ij]quinolines](/preview/png/5279002.png "First Page Preview: C-N bond forming reaction under copper catalysis: a new synthesis of 2-substituted 5,6-dihydro-4H-pyrrolo[3,2,1-ij]quinolines")
Authors
Mohosin Layek, A.V. Dhanunjaya Rao, Vikas Gajare, Dipak Kalita, Deepak Kumar Barange, Aminul Islam, K. Mukkanti, Manojit Pal,