Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5279008 | Tetrahedron Letters | 2009 | 4 Pages |
Abstract
A new strategy for the stereoselective synthesis of the 2,2â²-bipyrrolidine scaffold is presented using a metathesis reaction followed by asymmetric dihydroxylation for the introduction of the stereogenic elements. This straightforward high-yielding process is suitable for application to the synthesis of additional heterocycles.
Graphical abstractA new strategy for the stereoselective synthesis of the 2,2â²-bipyrrolidine scaffold is presented using a metathesis reaction followed by asymmetric dihydroxylation for the introduction of the stereogenic elements. This straightforward high-yielding process is suitable for application to the synthesis of additional heterocycles.Download full-size image
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Mary J. Gresser, Paul A. Keller, Steven M. Wales,