Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5279048 | Tetrahedron Letters | 2005 | 4 Pages |
Abstract
A simple, clean and highly efficient solvent-free procedure for the preparation of primary, secondary, tertiary and aromatic amides is described from the direct reaction of carboxylic acids and silica-supported ammonium salts, triethylamine (TEA) and tosyl chloride (TsCl) as condensing agent. The reaction proceeds rapidly in high yields at room temperature.
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Ali Khalafi-Nezhad, Abolfath Parhami, Mohammad Navid Soltani Rad, Abdolkarim Zarea,