| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5279129 | Tetrahedron Letters | 2011 | 4 Pages |
Abstract
4-Chloro-3-(trifluoroacetyl)coumarin was synthesized for the first time via direct TMSCl-mediated acylation of 4-hydroxycoumarin with TFAA followed by the treatment with POCl3. The reaction of 4-chloro-3-(trifluoroacetyl)coumarin with commercially available anilines is a two-step method, which affords a set of 7-(trifluoromethyl)-6H-chromeno[4,3-b]quinolin-6-ones in good to excellent yields.
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
![4-Chloro-3-(trifluoroacetyl)coumarin as a novel building block for the synthesis of 7-(trifluoromethyl)-6H-chromeno[4,3-b]quinolin-6-ones](/preview/png/5279129.png "First Page Preview: 4-Chloro-3-(trifluoroacetyl)coumarin as a novel building block for the synthesis of 7-(trifluoromethyl)-6H-chromeno[4,3-b]quinolin-6-ones")
Authors
Viktor O. Iaroshenko, Sajid Ali, Tariq Mahmood Babar, Sergii Dudkin, Satenik Mkrtchyan, Nasim Hasan Rama, Alexander Villinger, Peter Langer,