| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5279143 | Tetrahedron Letters | 2011 | 4 Pages |
Abstract
A novel silyl group-directed anti-SN2Ⲡreaction of allylic alcohols under Mitsunobu reaction conditions is described. The Mitsunobu reaction of α-hydroxy-α-alkenylsilanes with a TBS or TIPS group gave the anti-SN2Ⲡproduct, in which regio- and stereochemical outcomes of the reaction depended on the steric bulkiness of the silyl group.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Masato Higashino, Naoko Ikeda, Tetsuro Shinada, Kazuhiko Sakaguchi, Yasufumi Ohfune,