Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5279324 | Tetrahedron Letters | 2010 | 4 Pages |
Abstract
The four-component coupling (4CC) of sugar hydroxyaldehyde, Meldrum's acid, isocyanide, and a secondary alcohol in dichloromethane has been accomplished at room temperature in a highly stereoselective manner to produce a novel class of carbohydrate derivatives, 5-oxo-perhydrofuro[3,2-b]pyrans in good yields with trans-selectivity. The stereochemistry of the products was assigned by various NMR experiments.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
B.V. Subba Reddy, Nilanjan Majumder, A.V. Hara Gopal, Deepak Chatterjee, A.C. Kunwar,