Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5279337 | Tetrahedron Letters | 2010 | 4 Pages |
Abstract
Stille-type carbonylative cross-couplings, employing palladium catalysis and Mo(CO)6 as the carbon monoxide carrier, were used for the preparation of deoxybenzoins. Straightforward transformations were conveniently performed in closed vessels at 100 °C, providing the products in good yields. Benzyl bromides and chlorides were used as coupling partners with aryl and heteroaryl stannanes. This mild three-component carbonylation employs the destabilizing agent DBU to promote smooth release of carbon monoxide from Mo(CO)6, which made this protocol operationally simple and minimized the formation of Stille diarylmethane products.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Jonas Sävmarker, Jonas Lindh, Peter Nilsson,