Article ID Journal Published Year Pages File Type
5279347 Tetrahedron Letters 2010 4 Pages PDF
Abstract

Total synthesis of the furano lignan (+)-veraguensin is described. The key steps involve a diastereoselective aldol-type condensation of an ester enolate having an α-chiral center with an aromatic aldehyde and a novel isomerization of the syn vicinal substituents on the furan ring via a ring opening-ring closing protocol.

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Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry
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