Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5279368 | Tetrahedron Letters | 2006 | 4 Pages |
Abstract
Unsymmetrically substituted cis-3,4-diarylpyrrolidines are synthesized in nearly 25% overall yields starting from 4-aryl-1,2,5,6-tetrahydropyridines by iterative reactions using the combination of m-chloroperoxybenzoic acid (MCPBA) and boron trifluoride etherate (BF3·OEt2) followed by Grignard addition, elimination and hydrogenation sequence.
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Meng-Yang Chang, Chun-Li Pai, Chun-Yu Lin,