| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5279370 | Tetrahedron Letters | 2006 | 4 Pages |
Abstract
Functionalized bicyclic enol-ethers and spiroketals are prepared by Pd catalyzed cycloisomerization of 3-C-alkynylfuranosyl derivatives. Cycloisomerization of differently substituted alkyne derivatives revealed a preference for 6-endo-dig cyclization over 5-exo-dig if the substituent is not sufficiently electron withdrawing. The scope of these cycloisomerizations has been further extended by integrating with conjugate addition.
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