| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5279393 | Tetrahedron Letters | 2006 | 4 Pages |
Abstract
N-Picolinoyl-(2S)-(diphenylhydroxymethyl)pyrrolidine was found to work as an organic activator in the reduction of aromatic imines to the corresponding amines by Cl3SiH. The highest selectivity was 80% ee. These are the first data showing that N-formyl group is not always essential as N-protecting group of pyrrolidine derivatives for the reduction of imines by Cl3SiH.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Osamu Onomura, Yoshimi Kouchi, Fumiaki Iwasaki, Yoshihiro Matsumura,