| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5279414 | Tetrahedron Letters | 2007 | 5 Pages |
Abstract
An efficient methodology for the preparation of a series of 2,3-disubstituted-quinazolin-4(3H)-ones is described via a three step reaction from anthranilic acid. The obtained results also reveal that microwave-assisted rapid decomposition of formamide under controlled conditions of power, temperature and time is a very convenient source of ammonia for the synthesis of 2-substituted-quinazolin-4(3H)-ones and other rings.
Graphical abstractAn efficient microwave-assisted methodology for the preparation of 2,3-substituted-quinazolin-4(3H)-ones from anthranilic acid and using formamide as an ammonia source is described.Download full-size image
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Ioannis K. Kostakis, Abdelhakim Elomri, Elisabeth Seguin, Mauro Iannelli, Thierry Besson,