Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5279451 | Tetrahedron Letters | 2007 | 4 Pages |
Abstract
Modified oligodeoxyribonucleotides (ODNs) involving two perylene moieties are synthesized. By using this ODN, one-base deletion can easily be distinguished with high sensitivity. In addition, emission color of the solution greatly changed so that the detection was possible even by naked eyes.
Graphical abstractPerylene-modified oligodeoxyribonucleotides are synthesized for the detection of deletion polymorphisms with high sensitivity on the basis of the change of monomer â excimer emission.Download full-size image
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Hiromu Kashida, Tomohiko Takatsu, Hiroyuki Asanuma,