Article ID Journal Published Year Pages File Type
5279451 Tetrahedron Letters 2007 4 Pages PDF
Abstract

Modified oligodeoxyribonucleotides (ODNs) involving two perylene moieties are synthesized. By using this ODN, one-base deletion can easily be distinguished with high sensitivity. In addition, emission color of the solution greatly changed so that the detection was possible even by naked eyes.

Graphical abstractPerylene-modified oligodeoxyribonucleotides are synthesized for the detection of deletion polymorphisms with high sensitivity on the basis of the change of monomer → excimer emission.Download full-size image

Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry
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