| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5279475 | Tetrahedron Letters | 2009 | 4 Pages |
Abstract
A convergent synthesis of a unimolecular pentavalent-MUC1 glycopeptide has been accomplished. A tandem repeat of unglycosylated human tumor-associated MUC1, a potential target for cancer immunotherapy, was incorporated into the known unimolecular pentavalent carbohydrate construct (5). This is an important step toward the development of a new fully synthetic anticancer vaccine candidate (1).
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Dongjoo Lee, Samuel J. Danishefsky,