| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5279583 | Tetrahedron Letters | 2006 | 5 Pages |
Abstract
Vinyl and diene derivatives of thiolactomycin have been prepared via Horner-Wadsworth-Emmons olefination from protected 5-formyl-3,5-dimethylthiotetronic acid. Several 4-position protecting groups and a variety of phosphonates were evaluated, with MOM protection and β-ketophosphonates yielding the highest ratio of the desired product to deformylated product.
Related Topics
Physical Sciences and Engineering
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Authors
Pilho Kim, Clifton E. III, Cynthia S. Dowd,