Article ID Journal Published Year Pages File Type
5279592 Tetrahedron Letters 2006 4 Pages PDF
Abstract

The first successful attempt at synthesizing the 11-membered ring of madangamine alkaloids is described. The synthesis involves intramolecular N,O-acetalization of a cyclohexanone derivative, cross-coupling reaction with (Z)-vinylstannane, and intramolecular reductive amination for elaboration of the 11-membered macrocycle.

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Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry
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