| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5279608 | Tetrahedron Letters | 2009 | 5 Pages |
Abstract
This Letter describes an alternative protocol for the Michael addition of thiols to 4-hydroxy-2-alkynoates. The reaction proceeds at room temperature in water under ultrasound irradiation. With amines instead of thiols a sequential conjugate addition/lactonization reaction leads to important 4-amino-furan-2-one derivatives.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Antonio Arcadi, Maria Alfonsi, Fabio Marinelli,