Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5279631 | Tetrahedron Letters | 2009 | 4 Pages |
Abstract
We have developed a number of efficient protocols for the facile synthesis of 1,2,3,4-tetrahydroisoquinolin-1-ones. This synthetic methodology allowed concise and efficient exploration of the SAR in all areas of the molecule. A number of these methods proved to be versatile, efficient and amenable to parallel synthesis.
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Paul S. Humphries, Gayatri Balan, Bruce M. Bechle, Edward L. Conn, Kenneth J. Dirico, Yu Hui, Robert M. Oliver, James A. Southers, Xiaojing Yang,