Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5279694 | Tetrahedron Letters | 2005 | 6 Pages |
Abstract
The solution structure of the microtubule-stabilizing anti-cancer agent laulimalide, together with a series of simplified structural analogues, was determined by a combination of high field 1H NMR spectroscopic studies and constrained molecular dynamics simulations.
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Ian Paterson, Dirk Menche, Robert Britton, Anders E. HÃ¥kansson, MarıÌa Á. Silva-MartıÌnez,