| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5279726 | Tetrahedron Letters | 2007 | 4 Pages |
Abstract
Several vulpinic acids were synthesized in a few steps from a single precursor, the tetronic acid. This commercial compound was converted in a few steps to an iodide. Suzuki-Miyaura cross-couplings involving this common intermediate and various arylboronates allowed to gain access to several vulpinic acids (or methyl pulvinates). Among them, two natural products, vulpinic acid and pinastric acid, were prepared.
Graphical abstractTetronic acid was converted in a few steps to an alkenyl iodide which served as a common precursor for several vulpinic acids (methyl pulvinates), bearing different Ar groups, and obtained via Suzuki-Miyaura cross-couplings.Download full-size image
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Catherine Willis, Ewen Bodio, Yann Bourdreux, Célia Billaud, Thierry Le Gall, Charles Mioskowski,