Article ID Journal Published Year Pages File Type
5279732 Tetrahedron Letters 2007 4 Pages PDF
Abstract
Sulfated zirconia (SO4/ZrO2) catalyzed Mannich-type reactions of ketene silyl acetals and aldimines proceeded smoothly at room temperature to afford β-amino esters in good to high yields. In addition, the heterogeneous solid acid catalyst SO4/ZrO2 was easily recovered from the reaction mixture and then reused without significant loss of effectiveness.
Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry
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