| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5279749 | Tetrahedron Letters | 2007 | 4 Pages |
Abstract
In this study, the challenging Pd(0)-catalyzed Nα-Aloc removal from a proline residue using Me2NH·BH3 or PhSiH3 as allyl scavengers has been investigated. Standard conditions led to a large amount of an allylamine byproduct. A careful study of the reactions allowed us to design the optimal conditions for the quick and quantitative formation of the desired product, while taking advantage of a synergic effect between hydride and proton donors.
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Isidore P. Decostaire, Dominique Lelièvre, Vincent Aucagne, Agnès F. Delmas,