| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5279759 | Tetrahedron Letters | 2007 | 5 Pages |
Abstract
Propargyl 1,2-orthoesters are identified as glycosyl donors. Various glycosides and disaccharides were synthesized in a stereoselective manner using AuBr3 as the promoter. AuBr3 may activate the alkyne resulting in the formation of a 1,2-dioxolenium ion and also behaves as a Lewis acid to facilitate the attack of the glycosyl acceptor. The versatility of the protocol was demonstrated using a panel of aglycones comprising aliphatic, alicyclic, steroidal and sugar alcohols.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Gopalsamy Sureshkumar, Srinivas Hotha,