Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5279763 | Tetrahedron Letters | 2007 | 4 Pages |
Abstract
A novel auxillary chiral ketone has been designed, synthesized, and used to enantioselectively recognize 1,2-amino alcohols. This work proves that the keto group can serve as a chiral recognition center by imine formation supported by resonance assisted hydrogen bonding (RAHB).
Graphical abstractA novel auxillary chiral ketone has been designed, synthesized and used to enantioselectively recognize 1,2-amino alcohols. This work proves that the keto group can serve as a chiral recognition center by imine formation supported by resonance assisted hydrogen bonding (RAHB).Download full-size image
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Raju Nandhakumar, Yong-En Guo, Hyunjung Park, Lijun Tang, Wonwoo Nam, Kwan Mook Kim,