Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5279793 | Tetrahedron Letters | 2006 | 5 Pages |
Abstract
The first systematic screening of chiral phosphines in the cycloaddition reaction between 2,3-butadienoates and arylimines has led to the identification of fairly efficient catalysts. 2-Aryl-3-pyrrolines have been obtained with enantiomeric excesses up to 64%. In one instance, the enantiomeric excess could be increased to 91% ee by combining the enantioselective cyclization reaction with a crystallization step.
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Ludovic Jean, Angela Marinetti,