| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5279797 | Tetrahedron Letters | 2006 | 4 Pages |
Abstract
4-Quinolyl isothiocyanates were synthesized in a regiospecific fashion from the corresponding 4-chloroquinolines and silver thiocyanate in refluxing toluene. The products were isolated in quantitative yield and high purity (>95%) by simple filtration and concentration. Reactivity and mechanism of the reaction are discussed. The new approach would provide a new mean which had been lacking for the synthesis of functionalized 4-quinolinyl isothiocyanate.
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Boyu Zhong, Rima S. Al-Awar, Chuan Shih, John H. Jr., Michal Vieth, Chafiq Hamdouchi,