Article ID Journal Published Year Pages File Type
5279859 Tetrahedron Letters 2005 4 Pages PDF
Abstract

PEG-supported 2-methylphenacyl ester as a new photocleavable linker is reported. The photocleavage based on an efficient intramolecular hydrogen abstraction was carried out with 280-366 nm UV irradiation in benzene or methanol to give the corresponding carboxylic acid in high yields and purities. The linker was suitable for aliphatic and aromatic carboxylic acids as well as protected amino acids.

Graphical abstractPEG-supported 2-methylphenacyl ester as a new photocleavable linker is reported.Download full-size image

Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry
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