| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5279910 | Tetrahedron Letters | 2010 | 4 Pages |
Abstract
In an effort to decrease the toxicity and improve the stability of the E-ring of camptothecin, new analogues with an 'inverted' lactone ring were designed and synthesised. The compounds retained a good cytotoxic activity on human non-small lung cancer cells H-460.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Salvatore Cananzi, Sabrina Dallavalle, Alberto Bargiotti, Lucio Merlini, Roberto Artali, Giovanni Luca Beretta,