Article ID Journal Published Year Pages File Type
5279972 Tetrahedron Letters 2007 6 Pages PDF
Abstract

The highly chemo- and enantioselective organocatalytic [C+NC+CC] coupling process between aldehydes, dialkyl 2-aminomalonates and α,β-unsaturated aldehydes is presented. The reaction gives access to highly functionalized pyrrolidine derivatives in good yields with >10:1 dr and 90-98% ee.

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Physical Sciences and Engineering Chemistry Organic Chemistry
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