Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5279972 | Tetrahedron Letters | 2007 | 6 Pages |
Abstract
The highly chemo- and enantioselective organocatalytic [C+NC+CC] coupling process between aldehydes, dialkyl 2-aminomalonates and α,β-unsaturated aldehydes is presented. The reaction gives access to highly functionalized pyrrolidine derivatives in good yields with >10:1 dr and 90-98% ee.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Ismail Ibrahem, Ramon Rios, Jan Vesely, Armando Córdova,